Journal article

The RUNX3 tumor suppressor upregulates Bim in gastric epithelial cells undergoing transforming growth factor beta-induced apoptosis

Takashi Yano, Kosei Ito, Hiroshi Fukamachi, Xin-Zi Chi, Hee-Jun Wee, Ken-ichi Inoue, Hiroshi Ida, Philippe Bouillet, Andreas Strasser, Suk-Chul Bae, Yoshiaki Ito

Mol. Cell. Biol. | AMER SOC MICROBIOLOGY | Published : 2006

DOI: 10.1128/MCB.01926-05

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Keywords

Transcription Factors
Apoptosis
Transforming Growth Factor Beta
Gastric Mucosa
Mice
Active Transport, Cell Nucleus
Biochemistry & Molecular Biology
Bcl-2 Family-Member
Hypermethylation
Dna
Smad-Dependent Expression
Core Binding Factor Alpha 3 Subunit
Animals
Cell Biology
Smad Proteins
Tgf-Beta
Apoptosis Regulatory Proteins
Mice, Inbred Balb C
Membrane Proteins
Humans
Mice, Nude
Cancer
Mutagenesis, Site-Directed
Gene
Up-Regulation
Cloning
Base Sequence
Proto-Oncogene Proteins
Bcl-2-Like Protein 11
Stomach Neoplasms
Life Sciences & Biomedicine
Protein
Mice, Inbred C57bl
Cell Line, Tumor
Epithelial Cells
Promoter Regions, Genetic
Mice, Knockout
Science & Technology
Cooperation