Journal article
EGL-1 BH3 mutants reveal the importance of protein levels and target affinity for cell-killing potency
EF Lee, L Chen, H Yang, PM Colman, DCS Huang, WD Fairlie
Cell Death Differ. | NATURE PUBLISHING GROUP | Published : 2008
DOI: 10.1038/cdd.2008.86
Grants
Awarded by Australian NHMRC
Awarded by US NCI
Awarded by Leukemia and Lymphoma Society
Awarded by Cancer Council of Victoria
Awarded by NATIONAL CANCER INSTITUTE
Funding Acknowledgements
We thank H Ierino, K Knezevic and M Evangelista for technical assistance; R Anderson, S Korsmeyer, N Motoyama, C Thompson, and W Welch for reagents and A Strasser, P Bouillet, P Kelly and M van Delft for the mcl-f<SUP>-/-</SUP> cells. This work was supported by grants from the Australian NHMRC (Program Grant 257502), US NCI (CA80188), Leukemia and Lymphoma Society (Specialized Center of Research 7015-02), the Cancer Council of Victoria (Project 461239), fellowships and scholarships from the NHMRC (DCSH, WDF, PMC) and the Cancer Council of Victoria (PMC - Fraser Fellowship, EFL).