Journal article
Vasodilatory capacity of the coronary microcirculation is preserved in selected patients with non-ST-segment-elevation myocardial infarction
J Layland, D Carrick, M McEntegart, N Ahmed, A Payne, J McClure, A Sood, R McGeoch, A MacIsaac, R Whitbourn, A Wilson, K Oldroyd, C Berry
Circulation Cardiovascular Interventions | Published : 2013
Abstract
Background-The use of fractional flow reserve in patients with non-ST-segment-elevation myocardial infarction (NSTEMI) is a controversial issue. We undertook a study to assess the vasodilatory capacity of the coronary microcirculation in patients with NSTEMI when compared with a model of preserved microcirculation (stable angina [SA] cohort: culprit and nonculprit vessel) and acute microcirculatory dysfunction (ST-segment-elevation myocardial infarction [STEMI] cohort). We hypothesized that the vasodilatory response of the microcirculation would be preserved in NSTEMI. Methods and Results-A total of 140 patients undergoing single vessel percutaneous coronary intervention were included: 50 st..
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Awarded by British Heart Foundation
Funding Acknowledgements
This research was supported by grants from the British Heart Foundation (PG 11/2/2874) and Chief Scientist Office, Scottish Health Department.