Journal article

Vasodilatory Capacity of the Coronary Microcirculation is Preserved in Selected Patients With Non-ST-Segment-Elevation Myocardial Infarction

Jamie Layland, David Carrick, Margaret McEntegart, Nadeem Ahmed, Alex Payne, John McClure, Arvind Sood, Ross McGeoch, Andrew MacIsaac, Robert Whitbourn, Andrew Wilson, Keith Oldroyd, Colin Berry

CIRCULATION-CARDIOVASCULAR INTERVENTIONS | LIPPINCOTT WILLIAMS & WILKINS | Published : 2013

Abstract

BACKGROUND: The use of fractional flow reserve in patients with non-ST-segment-elevation myocardial infarction (NSTEMI) is a controversial issue. We undertook a study to assess the vasodilatory capacity of the coronary microcirculation in patients with NSTEMI when compared with a model of preserved microcirculation (stable angina [SA] cohort: culprit and nonculprit vessel) and acute microcirculatory dysfunction (ST-segment-elevation myocardial infarction [STEMI] cohort). We hypothesized that the vasodilatory response of the microcirculation would be preserved in NSTEMI. METHODS AND RESULTS: A total of 140 patients undergoing single vessel percutaneous coronary intervention were included: 50 ..

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