Targeting BCL-2 with the BH3 Mimetic ABT-199 in Estrogen Receptor-Positive Breast Cancer

Francois Vaillant; Delphine Merino; Lily Lee; Kelsey Breslin; Bhupinder Pal; Matthew E Ritchie; Gordon K Smyth; Michael Christie; Louisa J Phillipson; Christopher J Burns; G Bruce Mann; Jane E Visvader; Geoffrey J Lindeman

Journal article

Targeting BCL-2 with the BH3 Mimetic ABT-199 in Estrogen Receptor-Positive Breast Cancer

Francois Vaillant, Delphine Merino, Lily Lee, Kelsey Breslin, Bhupinder Pal, Matthew E Ritchie, Gordon K Smyth, Michael Christie, Louisa J Phillipson, Christopher J Burns, G Bruce Mann, Jane E Visvader, Geoffrey J Lindeman

Cancer Cell | CELL PRESS | Published : 2013

DOI: 10.1016/j.ccr.2013.06.002

University of Melbourne Researchers

Delphine Merino Author Medical Biology (W.E.H.I.)

Francois Vaillant Author Medical Biology (W.E.H.I.)

Christopher Burns Author Chemistry

Jane Visvader Author Medical Biology (W.E.H.I.)

Matthew Ritchie Author Medical Biology (W.E.H.I.)

Grants

Awarded by National Health and Medical Research Council, Australia (NHMRC)

Funding Acknowledgements

This work was supported by the National Health and Medical Research Council, Australia (NHMRC: 461221 and 1016701); NHMRC IRIISS; the Victorian State Government through Victorian Cancer Agency funding of the Victorian Breast Cancer Research Consortium and Operational Infrastructure Support; the Australian Cancer Research Foundation; The National Breast Cancer Foundation (NBCF); and the Qualtrough Family Bequest. J.E.V. was supported by a NHMRC Australia Fellowship, G.K.S. and G.J.L. by NHMRC Research Fellowships, and D.M. by a NBCF Early Career Fellowship.