Journal article

The effects, safety and acceptability of compact, pre-filled, autodisable injection devices when delivered by lay health workers

Claire Glenton, Rajesh Khanna, Chris Morgan, Elin Stromme Nilsen

Tropical Medicine & International Health | WILEY | Published : 2013


OBJECTIVES: To systematically assess (i) the effects and safety and (ii) the acceptability of using lay health workers (LHWs) to deliver vaccines and medicines to mothers and children through compact pre-filled autodisable devices (CPADs). METHODS: We searched electronic databases and grey literature. For the systematic review of effects and safety, we sought randomised and non-randomised controlled trials, controlled before-after studies and interrupted time series studies. For the systematic review of acceptability, we sought qualitative studies. Two researchers independently carried out data extraction, study quality assessment and thematic analysis of the qualitative data. RESULTS: No st..

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Funding Acknowledgements

We acknowledge Marit Johansen and Miwako Segawa for their help with the development and implementation of the search strategy, Rintaro Mori for providing feedback on the final methodology and search strategy and Metin Gulmezoglu for his help with the development of the review concept. We would also like to acknowledge The Norwegian Agency for Development Cooperation (NORAD) for their financial support. The Burnet Institute acknowledges the contribution of the Victorian Operational Infrastructure Support Program. In memory of co-author Elin Stromme Nilsen, who sadly died before the publication of this paper and will be sorely missed.