Metabolic outcomes in young children with type 1 diabetes differ between treatment centers: The Hvidoere study in young children 2009

CE De Beaufort; K Lange; PG Swift; J Aman; F Cameron; L Castano; H Dorchy; LK Fisher; H Hoey; E Kaprio; M Kocova; A Neu; PR Njolstad; M Phillip; E Schoenle; JJ Robert; T Urukami; M Vanelli; T Danne; T Barrett; F Chiarelli; HJ Aanstoot; HB Mortensen

Journal article

Metabolic outcomes in young children with type 1 diabetes differ between treatment centers: The Hvidoere study in young children 2009

CE De Beaufort, K Lange, PG Swift, J Aman, F Cameron, L Castano, H Dorchy, LK Fisher, H Hoey, E Kaprio, M Kocova, A Neu, PR Njolstad, M Phillip, E Schoenle, JJ Robert, T Urukami, M Vanelli, T Danne, T Barrett Show all

Pediatric Diabetes | Published : 2013

DOI: 10.1111/j.1399-5448.2012.00922.x

Abstract

Objective: To investigate whether center differences in glycemic control are present in prepubertal children <11yr with type 1 diabetes mellitus. Research Design and Methods: This cross-sectional study involved 18 pediatric centers worldwide. All children, <11 y with a diabetes duration ≥12months were invited to participate. Case Record Forms included information on clinical characteristics, insulin regimens, diabetic ketoacidosis (DKA), severe hypoglycemia, language difficulties, and comorbidities. Hemoglobin A1c (HbA1c) was measured centrally by liquid chromatography (DCCT aligned, range: 4.4-6.3%; IFFC: 25-45mmol/mol). Results: A total of 1133 children participated (mean age: 8.0±2.1 y; f..

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