Journal article
Clinical application of the 70-gene profile: The MINDACT trial
F Cardoso, L Van't Veer, E Rutgers, S Loi, S Mook, MJ Piccart-Gebhart
Journal of Clinical Oncology | Published : 2008
Abstract
The 70-gene profile is a new prognostic tool that has the potential to greatly improve risk assessment and treatment decision making for early breast cancer. Its prospective validation is currently ongoing through the MINDACT (Microarray in Node-Negative Disease May Avoid Chemotherapy) trial, a 6,000-patient randomized, multicentric trial. This article reviews the several steps in the development of the profile from its discovery to its clinical validation. © 2008 by American Society of Clinical Oncology.
Grants
Awarded by Cancer Research UK