Interleukin-11 Is the Dominant IL-6 Family Cytokine during Gastrointestinal Tumorigenesis and Can Be Targeted Therapeutically
Tracy L Putoczki, Stefan Thiem, Andrea Loving, Rita A Busutti, Nicholas J Wilson, Paul K Ziegler, Paul M Nguyen, Adele Preaudet, Ryan Farid, Kirsten M Edwards, Yeliz Boglev, Rodney B Luwor, Andrew Jarnicki, David Horst, Alex Boussioutas, Joan K Heath, Oliver M Sieber, Irina Pleines, Benjamin T Kile, Andrew Nash Show all
Cancer Cell | CELL PRESS | Published : 2013
Awarded by Australian Government NHMRC project
Awarded by Cancer Australia priority driven research scheme, Cure Cancer Australia
Awarded by Deutsche Krebshilfe
We thank R. Hughan, C. Dijkstra, C. Nowell, J. Corbin, and the LICR Animal Facility and Histology staff for excellent technical assistance. We thank A. Strasser, T. Rowe, M. Griffin, and B. Klopcic for critical review of the manuscript and P. Waring and M. Christie for pathological assessment of the mouse and human histology, respectively. A cohort of the de-identified human GC tissue was provided by the Victorian Cancer Biobank. This work was made possible through Victorian State Government Operational Infrastructure Support and Australian Government NHMRC project grant 1008614 and program grants 487922 and 1016647. T.L.P. also received funding from the Cancer Australia priority driven research scheme, Cure Cancer Australia grant 603121. P.K.Z. was supported by a doctoral fellowship from the Deutsche Krebshilfe (110114). M.E., B.T.K., and J.K.H. are Senior Research Fellows of the NHMRC. N.J.W., K.M.E., A.N., and B.S.M. are employees of CSL, Ltd., and T.L.P. and M.E. received research support from CSL, Ltd.