Journal article
Sinus rhythm restores ventricular function in patients with cardiomyopathy and no late gadolinium enhancement on cardiac magnetic resonance imaging who undergo catheter ablation for atrial fibrillation
LH Ling, AJ Taylor, AH Ellims, LM Iles, AJA McLellan, G Lee, S Kumar, G Lee, A Teh, C Medi, DM Kaye, JM Kalman, PM Kistler
Heart Rhythm | ELSEVIER SCIENCE INC | Published : 2013
Abstract
Background Atrial fibrillation (AF) and systolic heart failure (HF) frequently coexist. Restoration of sinus rhythm by catheter ablation may result in a variable improvement in left ventricular (LV) function. Late-gadolinium enhancement (LGE) on cardiac magnetic resonance (CMR) imaging identifies irreversible structural change and may predict incomplete recovery of LV function. Objective To prospectively select patients with AF and symptomatic HF but without LV LGE and report the impact of AF ablation on LV function. Methods Patients with AF and symptomatic HF (LV ejection fraction <50%) resistant to at least 1 antiarrhythmic drug and prior electrical cardioversion underwent contrast-enhance..
View full abstractGrants
Funding Acknowledgements
This research was supported in part by the Victorian Government's Operational Infrastructure Funding. Dr Ling is supported by an Australian National Heart Foundation (NHF) postgraduate scholarship. Dr Ellims, Dr McLellan, and Dr Kumar are supported by a cofounded National Health and Medical Research Council of Australia (NHMRC)/NHF postgraduate scholarship. Dr tics is supported by an NHMRC postgraduate research scholarship. Dr Kistler is supported by a practitioner fellowship from the NHMRC.