Journal article
Creating conductive structures for cell growth: Growth and alignment of myogenic cell types on polythiophenes
RD Breukers, KJ Gilmore, M Kita, KK Wagner, MJ Higgins, SE Moulton, GM Clark, DL Officer, RMI Kapsa, GG Wallace
Journal of Biomedical Materials Research Part A | Published : 2010
DOI: 10.1002/jbm.a.32822
Abstract
Conducting polymers provide suitable substrates for the in vitro study of excitable cells, including skeletal muscle cells, due to their inherent conductivity and electroactivity. The thiophene family of conducting polymers offers unique flexibility for tailoring of polymer properties as a result of the ease of functionalization of the parent monomer. This article describes the preparation of films and electrospun fibers from an ester-functionalized organic solvent-soluble polythiophene (poly-octanoic acid 2-thiophen-3-ylethyl ester) and details the changes in properties that result from post-polymerization hydrolysis of the ester linkage. The polymer films supported the proliferation and di..
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Funding Acknowledgements
The authors acknowledge the Australian Research Council (ARC) for funding of the ARC Centre of Excellence for Electromaterials Science (ACES) and G. G. Wallace Federation Fellowship. They thank Dr. Brianna Thompson for obtaining images presented in Figure 10.