Journal article

Oncogenic B-Raf(V600E) inhibits apoptosis and promotes ERK-dependent inactivation of Bad and Bim

Clare Sheridan, Gabriela Brumatti, Seamus J Martin

Journal of Biological Chemistry | AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC | Published : 2008

DOI: 10.1074/jbc.M800271200

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Keywords

Apoptosis
Bcl-Associated Death Protein
Bh3-Only Proteins
Protein Transport
Serine
Death
Mitochondrial-Membrane
Bcl-2-Associated X Protein
Proto-Oncogene Proteins
Hela Cells
Apoptosis Regulatory Proteins
Melanoma
Survival
Membrane Proteins
Point Mutation
Proto-Oncogene Proteins B-Raf
Biochemistry & Molecular Biology
Melanoma-Cells
Bcl-2-Like Protein 11
Therapeutic Target
Science & Technology
Mapk Signaling Pathway
Mitochondria
Humans
Life Sciences & Biomedicine
Bh3 Domains
B-Raf
Oncogenes
Cell Line, Tumor
Braf
Phosphorylation
Extracellular Signal-Regulated Map Kinases