Cysteine Oxidation within N-terminal Mutant Huntingtin Promotes Oligomerization and Delays Clearance of Soluble Protein
Jonathan H Fox, Teal Connor, Megan Stiles, Jibrin Kama, Zhen Lu, Kathryn Dorsey, Gregory Liebermann, Ellen Sapp, Robert A Cherny, Mary Banks, Irene Volitakis, Marian DiFiglia, Oksana Berezovska, Ashley I Bush, Steven M Hersch
Journal of Biological Chemistry | AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC | Published : 2011
Awarded by National Institutes of Health
This work was supported, in whole or in part, by National Institutes of Health Grants NS045806 (to S. H.), 5P20RR015640-10 (to University of Wyoming Neuroscience COBRE), and 1R21NS072372 (to J. F.). This work was also supported by Huntington's Disease Society of America awards (to S. H. (Coalition for the Cure) and J. F.) and also by the Cure Huntington's Disease initiative (to S. H.).