Journal article

A case-control study of lifetime occupational sitting and likelihood of breast cancer

BM Lynch, KS Courneya, CM Friedenreich

Cancer Causes and Control | Published : 2013

Abstract

Purpose Sedentary behavior may be a unique risk factor for some cancers, including breast cancer. The objective of this study was to determine the association between lifetime occupational sitting and likelihood of breast cancer. Methods A case-control study of 2,452 women was conducted in Alberta, Canada, between 1995 and 1997. A comprehensive measure of lifetime physical activity assessed frequency and duration of sedentary jobs. Logistic regression estimated the odds of being diagnosed with breast cancer across quartiles of lifetime occupational sitting, by menopausal status and family history of breast cancer, and within body mass index categories and physical activity quartiles. Results..

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University of Melbourne Researchers

Grants

Awarded by Alberta Cancer Board


Funding Acknowledgements

The authors acknowledge the contribution of Kathleen Douglas-England for study coordination; Zeva Mah, Laura Godard, Mila Belic, and Doreen Mandziuk for assistance with the research project; Lisa Alexander, Selena Chow, Pearl Cooke, Shelley Cooper, Linda Davison, Marilyn Dickson, Carrie Lavis, Doreen Mandziuk, Hijin Park, Jodi Parrotta, and Nicole Slot for interviewing the study participants; Valerie Hudson, Victoria Stagg, and Xuechao Chen for data cleaning and processing. This case-control study was funded by grants from the Canadian Breast Cancer Research Initiative (6442) and the Alberta Cancer Board Research Initiative Program (RI-107). Lynch is funded by a Public Health Training Fellowship from the National Health and Medical Research Council (586727); Courneya is supported by the Canada Research Chairs Program; Friedenreich is funded by a career award from the Alberta Innovates-Health Solutions and holds the Alberta Cancer Foundation Weekend to End Women's Cancers Breast Cancer Chair.