Diagnostic Imaging Agents for Alzheimer's Disease: Copper Radiopharmaceuticals that Target A beta Plaques

James L Hickey; SinChun Lim; David J Hayne; Brett M Paterson; Jonathan M White; Victor L Villemagne; Peter Roselt; David Binns; Carleen Cullinane; Charmaine M Jeffery; Roger I Price; Kevin J Barnham; Paul S Donnelly

Journal article

Diagnostic Imaging Agents for Alzheimer's Disease: Copper Radiopharmaceuticals that Target A beta Plaques

James L Hickey, SinChun Lim, David J Hayne, Brett M Paterson, Jonathan M White, Victor L Villemagne, Peter Roselt, David Binns, Carleen Cullinane, Charmaine M Jeffery, Roger I Price, Kevin J Barnham, Paul S Donnelly

Journal of the American Chemical Society | AMER CHEMICAL SOC | Published : 2013

DOI: 10.1021/ja4057807

University of Melbourne Researchers

Kevin Barnham Author Florey Department of Neuroscience and Mental Health

Jonathan White Author Chemistry

Paul Donnelly Author Chemistry

Peter Roselt Author Medicine - St Vincent's Hospital

Victor Villemagne Author Medicine - Austin Health

Related Projects (1)

Small Molecule X-ray Molecular Structure Elucidation Facility

X-ray diffraction plays a key role in identification and molecular characterisation. X-ray techniques are the single most widely used analyt..

Grants

Funding Acknowledgements

Financial support from the Australian Research Council and the National Health and Medical Research Council (Australia). The Victorian Brain Bank Network for the provision of human tissue. Clarity Pharmaceuticals for the provision of <SUP>64</SUP>CuCl<INF>2</INF>. Kerry Ardley and Susan Jackson for their technical expertise in performing the PET scanning and mouse biodistribution. Prof Rodney Hicks (Peter MacCallum Cancer Centre) for assistance in the interpretation of the small animal imaging.