Journal article

Identification of a rare coding variant in complement 3 associated with age-related macular degeneration

Xiaowei Zhan, David E Larson, Chaolong Wang, Daniel C Koboldt, Yuri V Sergeev, Robert S Fulton, Lucinda L Fulton, Catrina C Fronick, Kari E Branham, Jennifer Bragg-Gresham, Goo Jun, Youna Hu, Hyun Min Kang, Dajiang Liu, Mohammad Othman, Matthew Brooks, Rinki Ratnapriya, Alexis Boleda, Felix Grassmann, Claudia von Strachwitz Show all

Nature Genetics | NATURE PUBLISHING GROUP | Published : 2013


Awarded by US National Institutes of Health (National Eye Institute, National Human Genome Research Institute)

Awarded by Medical Research Council, UK

Awarded by Deutsche Forschungsgemeinschaft

Awarded by Medical Research Council

Awarded by National Institute for Health Research

Funding Acknowledgements

We thank all study participants for their generous volunteering. We thank B. Li, W. Chen, C. Sidore, T. Teslovich, L. Fritsche and M. Boehnke for useful discussion and suggestions. This project was supported by grants from the US National Institutes of Health (National Eye Institute, National Human Genome Research Institute; grants EY022005, HG007022, HG005552, EY016862, U54HG003079 and EY09859); the Medical Research Council, UK (grant G0000067); the Deutsche Forschungsgemeinschaft (grant WE1259/19-2); the Alcon Research Institute; The UK Department of Health's National Institute for Health Research (NIHR) Biomedical Research Centre for Ophthalmology at Moorfields Eye Hospital and the UCL Institute of Ophthalmology; Research to Prevent Blindness (New York); the Thome Memorial Foundation; the Harold and Pauline Price Foundation; and the National Health and Medical Research Council of Australia (NHMRC) Clinical Research Excellence (grant 529923, NHMRC practitioner fellowship 529905 and NHMRC Senior Research Fellowship 1028444). The study was also supported by the Intramural Research Program (Computational Medicine Initiative) of the National Eye Institute. The Centre for Eye Research Australia (CERA) receives operational infrastructure support from the Victorian Government. The views expressed in the publication are those of the authors and not necessarily those of their employers or the funders.