Journal article

Helsinki model cut stroke thrombolysis delays to 25 minutes in Melbourne in only 4 months

Atte Meretoja, Louise Weir, Melissa Ugalde, Nawaf Yassi, Bernard Yan, Peter Hand, Melinda Truesdale, Stephen M Davis, Bruce CV Campbell

NEUROLOGY | LIPPINCOTT WILLIAMS & WILKINS | Published : 2013

Abstract

OBJECTIVE: To test the transferability of the Helsinki stroke thrombolysis model that achieved a median 20-minute door-to-needle time (DNT) to an Australian health care setting. METHODS: The existing "code stroke" model at the Royal Melbourne Hospital was evaluated and restructured to include key components of the Helsinki model: 1) ambulance prenotification with patient details alerting the stroke team to meet the patient on arrival; 2) patients transferred directly from triage onto the CT table on the ambulance stretcher; and 3) tissue plasminogen activator (tPA) delivered in CT immediately after imaging. We analyzed our prospective, consecutive tPA registry for effects of these protocol c..

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Grants

Awarded by National Health and Medical Research Council of Australia (NHMRC) Centre for Research Excellence grant


Awarded by NHMRC Early Career Fellowship


Funding Acknowledgements

Supported by the National Health and Medical Research Council of Australia (NHMRC) Centre for Research Excellence grant 1001216. The authors received additional support from Finnish Medical, Biomedicum Helsinki, and Sigrid Juselius Foundations (A. M.), University of Melbourne, and Neurosciences Victoria (N.Y.), NHMRC Early Career Fellowship 1035688, Heart Foundation of Australia, National Stroke Foundation, and Cardiovascular Lipid Australia (B. C. V. C), and The Royal Melbourne Hospital Neurosciences Foundation (N.Y., B.C.V.C).