Journal article

Nanosecond-laser application in intermediate AMD: 12-month results of fundus appearance and macular function

Robyn H Guymer, Kate H Brassington, Peter Dimitrov, Galina Makeyeva, Malcolm Plunkett, Wie Xia, Devinder Chauhan, Algis Vingrys, Chi D Luu



BACKGROUND: A novel, ultra-low energy nanosecond laser (retinal rejuvenation therapy) has been developed with the aim to slow progression of early age-related macular degeneration (AMD). The safety, changes in fundus characteristics and macular function in a cohort of participants with bilateral intermediate AMD are reported. DESIGN: Prospective non-randomised, pilot intervention study. PARTICIPANTS OR SAMPLES: Subjects with bilateral intermediate AMD (n = 50, aged 50-75 years). METHODS: Ultra-low energy laser pulses applied in 12 spots around the macula of one eye (0.15-0.45 mJ), using 400 μm diameter spot, 3 nanosecond pulse length, 532 nm wavelength and energy titrated to each patient. MA..

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Awarded by National Health and Medical Research Council (NHMRC)

Awarded by NHMRC Centre for Clinical Research Excellence

Funding Acknowledgements

This work was supported by a grant to the Centre for Eye Research Australia, from the Victorian State Government under the Victoria's Science Agenda Investment Fund and from Ellex R&D Pty Ltd, Adelaide. RHG receives a National Health and Medical Research Council (NHMRC) practitioner fellowship (#529905). CERA is supported by a NHMRC Centre for Clinical Research Excellence #529923 award and receives operational infrastructure from the Victorian Government. The funding organizations had no role in the design or conduct of this research.