Journal article

Overview of evidence in prevention and aetiology of food allergy: A review of systematic reviews

CJ Lodge, KJ Allen, AJ Lowe, SC Dharmage

International Journal of Environmental Research and Public Health | Published : 2013

Abstract

The worldwide prevalence of food allergy appears to be increasing. Early life environmental factors are implicated in the aetiology of this global epidemic. The largest burden of disease is in early childhood, where research efforts aimed at prevention have been focused. Evidence synthesis from good quality systematic reviews is needed. We performed an overview of systematic reviews concerning the prevention and aetiology of food allergy, retrieving 14 systematic reviews, which covered three broad topics: formula (hydrolysed or soy) for the prevention of food allergy or food sensitization; maternal and infant diet and dietary supplements for the prevention of food allergy or food sensitizati..

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Grants

Funding Acknowledgements

The authors would like to thank Abhishek Easwaran for his contribution to the selection of studies, extraction of information and assessment of quality. Adrian J. Lowe and Shyamali C. Dharmage are supported by National Health and Medical Research Council of Australia (NHMRC), while Caroline J. Lodge is supported by the NHRMC funded Centre of Research Excellence in Food Allergy. Katrina J. Allen is supported by the Sylvia and Charles Viertel Charitable Foundation.