Plasminogen-stimulated airway smooth muscle cell proliferation is mediated by urokinase and annexin A2, involving plasmin-activated cell signalling

AG Stewart; YC Xia; T Harris; S Royce; JA Hamilton; M Schuliga

Journal article

Plasminogen-stimulated airway smooth muscle cell proliferation is mediated by urokinase and annexin A2, involving plasmin-activated cell signalling

AG Stewart, YC Xia, T Harris, S Royce, JA Hamilton, M Schuliga

BRITISH JOURNAL OF PHARMACOLOGY | WILEY-BLACKWELL | Published : 2013

DOI: 10.1111/bph.12422

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University of Melbourne Researchers

Simon Royce Author Clinical Pathology

John Hamilton Author Medicine - Royal Melbourne Hospital

Alastair Stewart Author Pharmacology and Therapeutics

Related Projects (1)

Characterising The Harmful Effects Of Urokinase In Asthma

The scarring of airway tissue in asthma increases the difficulty of breathing. There is no effective treatment for airway scarring in severe..

Grants

Awarded by NHMRC (Australia)

Funding Acknowledgements

We thank the Departments of Respiratory Medicine, Surgery, and Anatomical Pathology, Alfred Hospital, Australia and Professor Catriona MacClean for assistance in obtaining human biopsies. This work was supported by the NHMRC (Australia) research grant 1022048.