Journal article
STroke imAging pRevention and treatment (START): A longitudinal stroke cohort study: Clinical trials protocol
LM Carey, S Crewther, O Salvado, T Lindén, A Connelly, W Wilson, DW Howells, L Churilov, H Ma, T Tse, S Rose, S Palmer, P Bougeat, BCV Campbell, S Christensen, SL Macaulay, J Favaloro, V O' Collins, S Mcbride, S Bates Show all
International Journal of Stroke | Published : 2015
DOI: 10.1111/ijs.12190
Abstract
Rationale: Stroke and poststroke depression are common and have a profound and ongoing impact on an individual's quality of life. However, reliable biological correlates of poststroke depression and functional outcome have not been well established in humans. Aims: Our aim is to identify biological factors, molecular and imaging, associated with poststroke depression and recovery that may be used to guide more targeted interventions. Design: In a longitudinal cohort study of 200 stroke survivors, the START - STroke imAging pRevention and Treatment cohort, we will examine the relationship between gene expression, regulator proteins, depression, and functional outcome. Stroke survivors will be..
View full abstractGrants
Awarded by Australian Research Council
Funding Acknowledgements
The START program of research which comprised START_EXTEND (NTA 0901) and START_PrePARE (NTA 0902) is supported in part by the CSIRO of Australia through the Preventative Health Flagship Cluster. The National Stroke Research Institute, Florey Institute of Neuroscience and Mental Health acknowledges the support from the Operational Infrastructure Support Grant. We would particularly like to acknowledge the participants, clinician nurses, radiologists, study manager Ms Sue Bates, study coordinator Ms Elise Cowley, and START researchers (see http://www.START.csiro.au) who are contributing time and effort to the study. LMC is supported by an Australian Research Council Future Fellowship [number FT0992299]. The funding sources had no role in conduct of the study or writing of the report.