Journal article
Individualised pelvic floor muscle training in women with pelvic organ prolapse (POPPY): A multicentre randomized controlled trial
S Hagen, D Stark, C Glazener, S Dickson, S Barry, A Elders, H Frawley, MP Galea, J Logan, A McDonald, G McPherson, KH Moore, J Norrie, A Walker, D Wilson
Lancet | ELSEVIER SCIENCE INC | Published : 2014
Abstract
Background Pelvic organ prolapse is common and is strongly associated with childbirth and increasing age. Women with prolapse are often advised to do pelvic floor muscle exercises, but evidence supporting the benefits of such exercises is scarce. We aimed to establish the effectiveness of one-to-one individualised pelvic floor muscle training for reducing prolapse symptoms. Methods We did a parallel-group, multicentre, randomised controlled trial at 23 centres in the UK, one in New Zealand, and one in Australia, between June 22, 2007, and April 9, 2010. Female outpatients with newly-diagnosed, symptomatic stage I, II, or III prolapse were randomly assigned (1:1), by remote computer allocatio..
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Awarded by Chief Scientist Office
Funding Acknowledgements
Chief Scientist Office of the Scottish Government Health and Social Care Directorates, New Zealand Lottery Board, and National Health and Medical Research Council (Australia).The UK component of the trial was funded by the Chief Scientist Office (CSO) of the Scottish Government (project number CZH/4/377) and is summarised online. The Nursing, Midwifery and Allied Health Professions Research Unit and the Health Services Research Unit are also funded by the CSO. The views expressed in this publication are those of the investigators and not necessarily those of the CSO. We also acknowledge funding for the international components from the National Health and Medical Research Council (Australia) and the New Zealand Lottery Board. We accept full responsibility for the research. We thank all the women who willingly participated in the POPPY trial and completed their questionnaires and attended physiotherapy and gynaecology appointments; the staff at each of our centres for recruiting, motivating and treating our participants; the POPPY trial office staff in the UK (Kim Stewart and Lucy Pyart); those who administered the trial in Dunedin (Gaye Ellis) and Sydney (Wendy Allen) and members of the trial steering committee and data monitoring committee for giving their time in advising the trial team throughout the work.