Journal article

Type-1 interferon signaling mediates neuro-inflammatory events in models of Alzheimer's disease

Juliet M Taylor, Myles R Minter, Andrew G Newman, Moses Zhang, Paul A Adlard, Peter J Crack

Neurobiology of Aging | ELSEVIER SCIENCE INC | Published : 2014

DOI: 10.1016/j.neurobiolaging.2013.10.089

Grants

Funding Acknowledgements

This study was supported by grants from the National Health and Medical Research Council of Australia. PJC is an Australian Research Council Future Fellow.

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Keywords

Alpha
Animals
Inflammation
Neurotoxicity
Toll-Like Receptors
Cell Line
Phosphorylation
Microglia
Type-1 Interferons
Neuroblastoma
Disease Models, Animal
Polymerase Chain Reaction
Amyloid-Precursor-Protein
Cytokines
Interleukin-1β
Alzheimer'S Disease
Signal Transduction
Aged
Life Sciences & Biomedicine
Humans
Receptor, Interferon Alpha-Beta
Induce
Cell Death
Oxidative Stress
Mice
Neurosciences
Interferon Type I
Interleukin-6
Geriatrics & Gerontology
Interleukin-1 Beta
Molecular Targeted Therapy
Neurosciences & Neurology
Beta
Enzyme-Linked Immunosorbent Assay
Neurons
Brain
Mice, Transgenic
Alzheimer Disease
Apoptosis
Neuro-Inflammation
Amyloid Beta-Peptides
Science & Technology
Jak-Stat