Pressurized Pulse Irrigation with Saline Reduces Surgical-site Infections following Major Hepatobiliary and Pancreatic Surgery: Randomized Controlled Trial
Mehrdad Nikfarjam, Laurence Weinberg, Michael A Fink, Vijayaragavan Muralidharan, Graham Starkey, Robert Jones, Kevin Staveley-O'Carroll, Christopher Christophi
WORLD JOURNAL OF SURGERY | SPRINGER | Published : 2014
BACKGROUND: Surgical site infections (SSI) are a significant cause of postoperative morbidity. Pressurized pulse irrigation of subcutaneous tissues may lower infection rates by aiding in the debridement of necrotic tissue and reducing bacterial counts compared to simply pouring saline into the wound. METHODS: A total of 128 patients undergoing laparotomy extending beyond 2 h were randomized to treatment of wounds by pressurized pulse lavage irrigation (<15 psi) with 2 L normal saline (pulse irrigation group), or to standard irrigation with 2 L normal saline poured into the wound, immediately prior to skin closure (standard group). Only elective cases were included, and all cases were perform..View full abstract
This work was supported by a University of Melbourne, Early Career Developmental Grant, awarded to M.N. The study was not supported in any manner by Stryker, and there was no education or research contribution to the department or university.