Journal article
The physical anthropometry, lifestyle habits and blood pressure of people presenting with a first clinical demyelinating event compared to controls: The Ausimmune study
AL Ponsonby, RM Lucas, K Dear, I Van Der Mei, B Taylor, C Chapman, A Coulthard, T Dwyer, TJ Kilpatrick, AJ McMichael, MP Pender, PC Valery, D Williams
Multiple Sclerosis Journal | SAGE PUBLICATIONS LTD | Published : 2013
Abstract
Introduction: Lifestyle factors prior to a first clinical demyelinating event (FCD), a disorder often preceding the development of clinically definite multiple sclerosis (MS), have not previously been examined in detail. Past tobacco smoking has been consistently associated with MS. Methods: This was a multicentre incident case-control study. Cases (n = 282) were aged 18-59 years with an FCD and resident within one of four Australian centres (from latitudes 27°S to 43°S), from 1 November 2003 to 31 December 2006. Controls (n = 558) were matched to cases on age, sex and study region, without CNS demyelination. Exposures measured included current and past tobacco and marijuana, alcohol and bev..
View full abstractGrants
Awarded by National Multiple Sclerosis Society of the United States of America
Awarded by National Health and Medical Research Council of Australia
Funding Acknowledgements
The work was supported by the National Multiple Sclerosis Society of the United States of America (Award RG3364A1/2), the National Health and Medical Research Council of Australia (APP316901 and 224215), the Australian Research Council, The Royal Australasian College of Physicians, the ANZ William Buckland Foundation, Multiple Sclerosis Research Australia and Bayer Schering Pharma and Biogen Idec. Funding sources did not contribute to the design and conduct of the study, management, analysis or interpretation of the data or approval of the manuscript.