Oncogenic H-Ras Reprograms Madin-Darby Canine Kidney (MDCK) Cell-derived Exosomal Proteins Following Epithelial-Mesenchymal Transition

Bow J Tauro; Rommel A Mathias; David W Greening; Shashi K Gopal; Hong Ji; Eugene A Kapp; Bradley M Coleman; Andrew F Hill; Ulrike Kusebauch; Janice L Hallows; David Shteynberg; Robert L Moritz; Hong-Jian Zhu; Richard J Simpson

Journal article

Oncogenic H-Ras Reprograms Madin-Darby Canine Kidney (MDCK) Cell-derived Exosomal Proteins Following Epithelial-Mesenchymal Transition

Bow J Tauro, Rommel A Mathias, David W Greening, Shashi K Gopal, Hong Ji, Eugene A Kapp, Bradley M Coleman, Andrew F Hill, Ulrike Kusebauch, Janice L Hallows, David Shteynberg, Robert L Moritz, Hong-Jian Zhu, Richard J Simpson

Molecular and Cellular Proteomics | AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC | Published : 2013

DOI: 10.1074/mcp.M112.027086

University of Melbourne Researchers

Hongjian Zhu Author Surgery - Royal Melbourne Hospital

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Grants

Awarded by National Health & Medical Research Council (NHMRC) of Australia

Awarded by Australian Research Council

Awarded by Early Career CJ Martin Fellowship

Awarded by NHMRC Dora Lush Biomedical Postgraduate Scholarship

Awarded by National Health & Medical Research Council of Australia

Awarded by American Recovery and Reinvestment Act funds through National Institutes of Health

Awarded by NIGMS Grant from Center for Systems Biology

Awarded by National Science Foundation (MRI Grant)

Awarded by NCI of the NIH

Funding Acknowledgements

This work was supported by the National Health & Medical Research Council (NHMRC) of Australia for program grant #487922 (RJS, JH, DWG), grants #280913 and #433619 (H-JZ), grants #628946 and #400202 (AFH). AFH is also supported by an Australian Research Council (www.arc.gov.au) Future Fellowship (FT100100560). RAM is supported by an Early Career CJ Martin Fellowship #APP1037043, and BMC by an NHMRC Dora Lush Biomedical Postgraduate Scholarship #628959. BJT is supported by The University of Melbourne Research Scholarship. Analysis of proteomic data described in this work was supported using the Australian Proteomics Computational Facility funded by the National Health & Medical Research Council of Australia grant #381413. Electron microscopy was performed at the Advanced Microscopy Facility at the Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne. This work was also supported, in part, by American Recovery and Reinvestment Act funds through National Institutes of Health Grant R01 HG005805 (RLM), the NIGMS Grant 2P50 GM076547 from Center for Systems Biology, the Luxembourg Centre for Systems Biomedicine and the University of Luxembourg, and from the National Science Foundation (MRI Grant 0923536). UK was supported by a fellowship from the German Academic Exchange Service. We thank the NCI of the NIH for support (Grant #1R03CA156667 to RLM).