Journal article

Epistasis with HLA DR3 implicates the P2X7 receptor in the pathogenesis of primary Sjogren's syndrome

Susan Lester, Leanne Stokes, Kristen K Skarratt, Ben J Gu, Kathy L Sivils, Christopher J Lessard, James S Wiley, Maureen Rischmueller

ARTHRITIS RESEARCH & THERAPY | BIOMED CENTRAL LTD | Published : 2013

DOI: 10.1186/ar4248

Related Projects (1)

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Finding genes that cause multiple sclerosis and influence its progression

There is no cure for multiple sclerosis (MS), but a person's genetic make-up can influence their susceptibility to developing MS and the sym..

Grants

Awarded by National Health and Medical Research Council (NHMRC)

Funding Acknowledgements

This study was funded by support from Arthritis Australia, National Health and Medical Research Council (NHMRC, grant number 509184), and The Queen Elizabeth Hospital Research Foundation

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Keywords

Polymorphism
Epistasis, Genetic
Female
Autoantibodies
Systemic-Lupus-Erythematosus
Disease
P2x(7) Receptor
Purinergic Receptor
Enzyme-Linked Immunosorbent Assay
Humans
Ductal Cells
Life Sciences & Biomedicine
Receptors, Purinergic P2x7
Rheumatoid-Arthritis
Science & Technology
Male
Rheumatology
Ribonucleoproteins
Polymorphism, Single Nucleotide
Genotype
Interleukin-18
Il-1-Beta Release
Autoantigens
Extracellular Atp
Hla-Dr3 Antigen
Sjogren'S Syndrome
Antibodies, Antinuclear
Human Monocytes