Journal article

Atopic disorders and depression: Findings from a large, population-based study

Livia Sanna, Amanda L Stuart, Julie A Pasco, Felice N Jacka, Michael Berk, Michael Maes, Adrienne O'Neill, Paolo Girardi, Lana J Williams

JOURNAL OF AFFECTIVE DISORDERS | ELSEVIER SCIENCE BV | Published : 2014

Abstract

BACKGROUND: Atopy, a common disorder characterized by a sensitivity to allergic reactions, affects a large proportion of the adult population and, as with depression, is associated with immune-inflammatory pathway changes. We sought to determine the role of atopic disorders in depression using data from a randomly-selected, population-based study of men and women. METHODS: Cross-sectional data derived from the Geelong Osteoporosis Study for 942 males and 1085 females were analyzed. Depression [major depressive disorder (MDD), minor depression and dysthymia] was assessed using the Structured Clinical Interview for DSM-IV-TR Research Version, Non-patient edition. Data on medical conditions, in..

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Grants

Funding Acknowledgements

The study was funded by the National Health and Medical Research Council (NHMRC) of Australia. The authors acknowledge the men and women who participated in the study.