Journal article

Determining research priorities for clinician-initiated trials in infectious diseases

DL Paterson

Medical Journal of Australia | WILEY | Published : 2013

Abstract

Objectives: To determine research priorities of infectious diseases physicians for clinician-initiated randomised controlled trials (RCTs). Design, setting and participants: Online survey of infectious diseases physicians in Australia and New Zealand. Main outcome measures: Research priorities for, and perceived barriers to, clinician-initiated RCTs. Results: 122/550 infectious diseases physicians (22%) responded to the survey. The five highest ranked proposals for clinician-initiated RCTs were in the areas of prosthetic joint infections, septic arthritis and osteomyelitis of native joints, Staphylococcus aureus bloodstream infections, diabetic foot infections and the treatment of serious mu..

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Grants

Funding Acknowledgements

Tania Sorrell has received untied research funds from Gilead Sciences, Merck, Sharp & Dohme and Pfizer Pharmaceuticals and has been a member of their respective antifungal advisory boards Sharon Chen has served on the antifungal advisory boards of Pfizer Australia, Merck, Sharp & Dohme and Gilead Sciences and has received educational grants from Pfizer Australia, Merck, Sharp & Dohme and Gilead Sciences. Narin Bak has received financial sponsorship for travel-related educational meetings from Merck, Sharp & Dohme, Gilead Sciences and Pfizer and honoraria for educational lectures from Merck, Sharp & Dohme. He has undertaken clinical trials with antivirals and other antibiotics for many other pharmaceutical companies. David Paterson has served as a consultant or on advisory boards for AstraZeneca, Merck, Sharp & Dohme, Pfizer, Cubist, Leo Pharmaceuticals, Novartis, Johnson and Johnson, Bayer, Trius and Achaogen, and has received honoraria for educational lectures from AstraZeneca and research funds from Sanofi Aventis.