Journal article

Bio-ink properties and printability for extrusion printing living cells

JHY Chung, S Naficy, Z Yue, R Kapsa, A Quigley, SE Moulton, GG Wallace

Biomaterials Science | ROYAL SOC CHEMISTRY | Published : 2013

Abstract

Additive biofabrication (3D bioprinting) makes it possible to create scaffolds with precise geometries, control over pore interconnectivity and architectures that are not possible with conventional techniques. Inclusion of cells within the ink to form a "bio-ink" presents the potential to print 3D structures that can be implanted into damaged/diseased tissue to promote highly controlled cell-based regeneration and repair. The properties of an 'ink' are defined by its formulation and critically influence the delivery and integrity of structure formed. Importantly, the ink properties need to conform to biological requirements necessary for the cell system that they are intended to support and ..

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University of Melbourne Researchers

Grants

Awarded by NHMRC


Funding Acknowledgements

This research was supported by the Australian Research Council, Super Science Fellowship Scheme, ARC Centre for Electromaterials Science (ACES) and NHMRC (Project 573430). The authors would like to acknowledge the Australian National Fabrication Facility (ANFF) for funding of the equipments, EMC facility at University of Wollongong (Innovation campus) for microscopy analysis, Dr Stephen Beirne for the making of hydrogel moulds, ARC Fellowships to Gordon G. Wallace (Australian Laureate Fellow), and Simon E. Moulton (ARC QEII Fellow) are gratefully acknowledged.