Journal article

Is glycosylated haemoglobin associated with psychosocial stress in non-diabetic 6-year-olds?

AMH Price, T Maayan, MA Wake, H Hiscock

Journal of Paediatrics and Child Health | WILEY | Published : 2014

Abstract

Aim Glycosylated haemoglobin (HbA1c), a marker of diabetic glycemic control, is associated with chronic psychosocial stress in non-diabetic adults. This study aimed to determine whether HbA1c also acts as a biomarker of psychosocial stress in healthy 6-year-olds. Methods Design and participants: Eligible participants were 326 children recruited from 6 socio-economically diverse areas in Melbourne, Australia, who took part in an earlier randomised trial for sleep problems at age 7 months. At 6 years, they participated in a follow-up assessment. Outcome:â€...HbA1c collected by finger-prick. Exposures (collected simultaneously): proxy measures of child stress including: (i) child mental health;..

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University of Melbourne Researchers

Grants

Awarded by Australian National Health & Medical Research Council (NHMRC)


Awarded by follow-up Kids Sleep Study by the Foundation for Children


Awarded by NHMRC Population Health Career Development Awards


Awarded by NHMRC Population Health Capacity Building Grant


Funding Acknowledgements

The Infant Sleep Study was supported by the Australian National Health & Medical Research Council (NHMRC) Project Grant (Grant Number 237120) and the Pratt Foundation, and the follow-up Kids Sleep Study by the Foundation for Children (Grant Number 180 2009). The authors' work was independent of the funders (the funding source had no involvement). AP was supported by a Melbourne Research Scholarship (The University of Melbourne) and the Murdoch Childrens Research Institute (MCRI), MW by NHMRC Population Health Career Development Awards (Grant Numbers 284556 and 546405), and HH's postdoctoral position by NHMRC Population Health Capacity Building Grant (Grant Number 436914) and Career Development Award (Grant Number 607351). The MCRI administered the grants and provided infrastructural support to its staff but played no role in the conduct or analysis of the trial.