Journal article

Germline Variants and Advanced Colorectal Adenomas: Adenoma Prevention with Celecoxib Trial Genome-wide Association Study

Jiping Wang, Luis G Carvajal-Carmona, Jen-Hwa Chu, Ann G Zauber, Michikai Kubo, Koichi Matsuda, Malcolm Dunlop, Richard S Houlston, Oliver Sieber, Lara Lipton, Peter Gibbs, Nicholas G Martin, Grant W Montgomery, Joanne Young, Paul N Baird, Mark J Ratain, Yusuke Nakamura, Scott T Weiss, Ian Tomlinson, Monica M Bertagnolli

Clinical Cancer Research | AMER ASSOC CANCER RESEARCH | Published : 2013

Grants

Awarded by U.S. National Cancer Institute


Awarded by Medical Research Council


Awarded by ORE and Scottish Executive Chief Scientist's Office


Awarded by National Cancer Institute, NIH


Awarded by Australian Colorectal Cancer Family Registry


Awarded by USC Familial Colorectal Neoplasia Collaborative Group


Awarded by Mayo Clinic Cooperative Family Registry for Colon Cancer Studies


Awarded by Ontario Registry for Studies of Familial Colorectal Cancer


Awarded by Seattle Colorectal Cancer Family Registry


Awarded by University of Hawaii Colorectal Cancer Family Registry


Awarded by NCI


Awarded by Wellcome Trust


Awarded by Cancer Research UK


Funding Acknowledgements

The APC study was funded by the U.S. National Cancer Institute (CA-N01-95015 and HHSN261201000082C) and by Pfizer. Cancer Research UK funded the CORGI, Scotland, and NSCCG studies. L. G. Carvajal-Carmona is supported by the EU FP7 CHIBCHA project. I. Tomlinson received support from the Oxford NIHR Comprehensive Biomedical Research Centre. Core infrastructure support to the Wellcome Trust Centre for Human Genetics, Oxford was provided by grant 090532/Z/09/Z. The United Kingdom National Cancer Research Network supported the NSCCG. M. Dunlop received from the Medical Research Council (G0000657-53203), CORE and Scottish Executive Chief Scientist's Office (K/OPR/2/2/D333, CZB/4/449). The Colon Cancer Family Registry was supported by the National Cancer Institute, NIH under Request for Application # CA-95-011, and through cooperative agreements with the Australian Colorectal Cancer Family Registry (UO1 CA097735), the USC Familial Colorectal Neoplasia Collaborative Group (UO1 CA074799), Mayo Clinic Cooperative Family Registry for Colon Cancer Studies (UO1 CA074800), Ontario Registry for Studies of Familial Colorectal Cancer (UO1 CA074783), Seattle Colorectal Cancer Family Registry (UO1 CA074794), and The University of Hawaii Colorectal Cancer Family Registry (UO1 CA074806). P.N. Baird is supported by Australian National Health and Medical Research Council Senior Research Fellowship # 1028444. CERA receives Operational Infrastructure Support from the Victorian Government, Australia.This study was supported by NCI N01-95015 and HHSN261201000082C (to M. M. Bertagnolli, A. G. Zauber, and J. Wang), U01GM61393 (to M.J. Ratain), U01GM61390, and the Biobank Japan Project funded by the Japanese Ministry of Education, Culture, Sports, Science and Technology. This work is part of the NIH Pharmacogenomics Research Network-RIKEN Center for Genomic Medicine Global Alliance. Pfizer, Inc. partially funded the APC Trial. L. G. Carvajal-Carmona and I. Tomlinson received support from Cancer Research UK and the Oxford Comprehensive Biomedical Research Centre, and the European Union (FP7 CHIBCHA Consortium). The Wellcome Trust Centre for Human Genetics is supported by a Wellcome Trust Core Grant 090532/Z/09/Z.