Journal article

A genome-wide association study and biological pathway analysis of epilepsy prognosis in a prospective cohort of newly treated epilepsy

Doug Speed, Clive Hoggart, Slave Petrovski, Ioanna Tachmazidou, Alison Coffey, Andrea Jorgensen, Hariklia Eleftherohorinou, Maria De Iorio, Marian Todaro, Tisham De, David Smith, Philip E Smith, Margaret Jackson, Paul Cooper, Mark Kellett, Stephen Howell, Mark Newton, Raju Yerra, Meng Tan, Chris French Show all

Human Molecular Genetics | OXFORD UNIV PRESS | Published : 2014


Awarded by Wellcome Trust

Awarded by NIHR Biomedical Research Centres Scheme

Awarded by Medical Research Council

Awarded by Royal Melbourne Hospital Foundation Lottery Grants

Awarded by National Institute for Health Research

Funding Acknowledgements

This work was funded by the Wellcome Trust (WT066056 to M.R.J.), The NIHR Biomedical Research Centres Scheme (P31753 to M.R.J.), Department of Health NHS Chair of Pharmacogenetics (to M. P.), The Medical Research Council (REF: 25105 to D. B. and M.R.J.), The Royal Melbourne Hospital Foundation Lottery Grants (REF: 604955 to S. P.) and The RMH Neuroscience Foundation (to T.J.O'B.). M.R.J. conceived the UK study and coordinated the UK DNA collection. T.J.O'B. conceived the Australian study and coordinated the Australian DNA collection. M.R.J., D. C., M. P. and D. B. obtained the funding to collect the UK DNA samples. T.J.O'B. obtained the funding to collect Australian samples. M.R.J., D. C., M. P., D. B., A. P., A. M., S. P. and T.J.O'B. obtained the funding to genotype the samples. Genomic data were analysed by D. S., C. H., I. T., S. P., A.J., A. P., M. D., T. D. and M.R.J. DNA samples and phenotypic information was collected and analysed by S. P., A.J., M. T., D. S., P. E. S., P. C., M. K., S. H., M. R., G. E. S., D. C., M. P., I. S., S. B., A. M., I. S., S. B., M.N., R.Y., M. T., C. F. and M.R.J. D. S., C. H., S. P. and M.R.J. drafted the manuscript. All authors reviewed and edited the manuscript. M.R.J. confirms that he has full access to all the data in the study and has final responsibility for the decision to submit for publication.