PET imaging of tumours with a Cu-64 labeled macrobicyclic cage amine ligand tethered to Tyr(3)-octreotate
Brett M Paterson, Peter Roselt, Delphine Denoyer, Carleen Cullinane, David Binns, Wayne Noonan, Charmaine M Jeffery, Roger I Price, Jonathan M White, Rodney J Hicks, Paul S Donnelly
Dalton Transactions | ROYAL SOC CHEMISTRY | Published : 2014
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This work was partially supported by the Australian Research Council (PSD). Dr Matt Harris (Clarity Pharmaceuticals) is thanked for his support. We thank John A. Karas (Bio21 Institute, University of Melbourne) for guidance on peptide synthesis, and Kerry Ardley and Susan Jackson (Peter MacCallum Division of Molecular Imaging, Melbourne) for their technical contributions. The A427-7 cells were a kind donation from Prof Buck E. Rogers (Washington University, St Louis, MO). Professor Rod Hicks is a recipient of a translational research grant from the Victorian Cancer Agency which supported the in vitro and in vivo testing of this agent.