Journal article
Subtle post-procedural cognitive dysfunction after atrial fibrillation ablation
C Medi, L Evered, B Silbert, A Teh, K Halloran, J Morton, P Kistler, J Kalman
Journal of the American College of Cardiology | Published : 2013
Abstract
Objectives This study sought to determine whether post-operative neurocognitive dysfunction (POCD) occurs after ablation for atrial fibrillation (AF). Background Ablation for AF is a highly effective strategy; however, the risk of transient ischemic attack and stroke is approximately 0.5% to 1%. In addition, magnetic resonance imaging studies report a 7% to 14% prevalence of silent cerebral infarction. Whether cerebral ischemia results in POCD after ablation for AF is not well established. Methods The study included 150 patients; 60 patients undergoing ablation for paroxysmal atrial fibrillation (PAF), 30 patients undergoing ablation for persistent atrial fibrillation (PeAF), and 30 patients..
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Funding Acknowledgements
Drs. Medi and Teh are supported by a medical postgraduate scholarship from the National Heart Foundation of Australia; and was a recipient of a cardiovascular and lipid research grant from Pfizer. Prof. Kistler is supported in part by the Victorian Government's Operational Infrastructure Support Program. Prof. Kalman receives research and fellowship support from St. Jude Medical, Medtronic, and Biosense Webster. Dr. Medi received the Eric N. Prystowsky Fellow Clinical Research Award at the Heart Rhythm Society Meeting in Denver, Colorado, in 2010 for research presented in this paper. All other authors have reported that they have no relationships relevant to the content of this paper to disclose.