Relaxin-3/RXFP3 system regulates alcohol-seeking

Philip J Ryan; Hanna E Kastman; Elena V Krstew; K Johan Rosengren; Mohammed Akhter Hossain; Leonid Churilov; John D Wade; Andrew L Gundlach; Andrew J Lawrence

Journal article

Relaxin-3/RXFP3 system regulates alcohol-seeking

Philip J Ryan, Hanna E Kastman, Elena V Krstew, K Johan Rosengren, Mohammed Akhter Hossain, Leonid Churilov, John D Wade, Andrew L Gundlach, Andrew J Lawrence

Proceedings of the National Academy of Sciences of the United States of America | NATL ACAD SCIENCES | Published : 2013

DOI: 10.1073/pnas.1317807110

University of Melbourne Researchers

Andrew Gundlach Author Anatomy and Neuroscience

Akhter Hossain Author Florey Department of Neuroscience and Mental Health

Andrew Lawrence Author Florey Department of Neuroscience and Mental Health

Philip Ryan Author Florey Department of Neuroscience and Mental Health

John Wade Author Florey Department of Neuroscience and Mental Health

Related Projects (3)

How The Brain Regulates Reward

Substance abuse is a significant social and economic burden upon Australian societies and on societies around the world. Treatment remains p..

Peptide Neurotransmission In Mental Health And Psychiatric Illness

Our laboratory recently discovered the brain 'transmitter' called 'relaxin-3', and are researching how it affects brain activity and animal ..

Novel Strategies To Treat Alcohol And Drug Abuse

A key problem with alcoholism, as with addiction generally, is the chronically relapsing nature of the disorder. This can be modelled in rod..

Grants

Awarded by National Health and Medical Research Council of Australia

Funding Acknowledgements

We thank Elena Buchler (Zentralinstitut fur Seelische Gesundheit, Mannheim, Germany) and Shaun Khoo (University of New South Wales, Sydney) for technical assistance. These studies were supported in part by Project Grants 508976, 509246, and 1021227 from the National Health and Medical Research Council of Australia, of which J.D.W., A.L.G., and A.J.L. are Research Fellows. We acknowledge financial support from the Besen Family and Pratt Foundations and the Victorian Government's Operational Infrastructure Support Program. P.J.R. was supported by an Australian Postgraduate Award and a Dowd Foundation Scholarship. H.E.K. was supported by an Uppsala University Exchange Scholarship and a University of Melbourne International Scholarship.