Journal article
The natural history and clinical predictors of egg allergy in the first 2 years of life: A prospective, population-based cohort study
RL Peters, SC Dharmage, LC Gurrin, JJ Koplin, AL Ponsonby, AJ Lowe, MLK Tang, D Tey, M Robinson, D Hill, H Czech, L Thiele, NJ Osborne, KJ Allen
Journal of Allergy and Clinical Immunology | MOSBY-ELSEVIER | Published : 2014
Abstract
Background There is a paucity of data examining the natural history of and risk factors for egg allergy persistence, the most common IgE-mediated food allergy in infants. Objective We aimed to assess the natural history of egg allergy and identify clinical predictors for persistent egg allergy in a population-based cohort. Methods The HealthNuts study is a prospective, population-based cohort study of 5276 infants who underwent skin prick tests to 4 allergens, including egg. Infants with a detectable wheal were offered hospital-based oral food challenges (OFCs) to egg, irrespective of skin prick test wheal sizes. Infants with challenge-confirmed raw egg allergy were offered baked egg OFCs at..
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Funding Acknowledgements
Supported by the National Health & Medical Research Council (NHMRC) of Australia, the Ilhan Food Allergy Foundation, AnaphylaxiStop, the Charles and Sylvia Viertel Medical Research Foundation, the Victorian Government's Operational Infrastructure Support Program, and the Australian Egg Corporation Ltd. K.J.A. is a Viertel Senior Medical Research Fellow. R.L.P. is an Australian Postgraduate Award scholar. L.C.G., A.J.L., A.-L.P., J.J.K., and S.C.D. hold NHMRC awards.