Quantification of copper binding to amyloid precursor protein domain 2 and its Caenorhabditis elegans ortholog. Implications for biological function

Su Ling Leong; Tessa R Young; Kevin J Barnham; Anthony G Wedd; Mark G Hinds; Zhiguang Xiao; Roberto Cappai

Journal article

Quantification of copper binding to amyloid precursor protein domain 2 and its Caenorhabditis elegans ortholog. Implications for biological function

Su Ling Leong, Tessa R Young, Kevin J Barnham, Anthony G Wedd, Mark G Hinds, Zhiguang Xiao, Roberto Cappai

Metallomics: integrated biometal science | ROYAL SOC CHEMISTRY | Published : 2014

DOI: 10.1039/c3mt00258f

University of Melbourne Researchers

Anthony Wedd Author Chemistry

Kevin Barnham Author Florey Department of Neuroscience and Mental Health

Roberto Cappai Author Biochemistry and Pharmacology

Zhiguang Xiao Author Biochemistry and Pharmacology

Grants

Funding Acknowledgements

This work was funded by grants from the Australian Research Council and the National Health and Medical Research Council (NHMRC). RC and KJB are NHMRC Senior Research Fellows. NMR spectra were acquired at the Bio21 Institute NMR Facility, University of Melbourne. SLL is currently at Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, U.K.