Journal article
Regional white matter microstructure in very preterm infants: Predictors and 7 year outcomes
DK Thompson, KJ Lee, GF Egan, SK Warfield, LW Doyle, PJ Anderson, TE Inder
Cortex | Published : 2014
Abstract
The aims of this study were to investigate regional white matter microstructural differences between very preterm (VPT) (<30 weeks' gestational age and/or <1250g) and full term (FT) (®37 weeks' gestational age) infants at term corrected age with diffusion tensor imaging, and to explore perinatal predictors of diffusion measures, and the relationship between regional diffusion measures and neurodevelopmental outcomes at age 7 years in VPT children. Mean (MD) (p= .003), axial (AD) (p= .008), and radial diffusivity (RD) (p= .003) in total white matter were increased in VPT compared with FT infants, with similar fractional anisotropy (FA) in the two groups. There was little evidence that group-w..
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Awarded by National Institutes of Health
Funding Acknowledgements
This work was supported by the National Health and Medical Research Council of Australia [237117 and 546519 to L.W.D., 400317 to G.F.E., 628371 and 491209 to P.J.A., (the Australian Postgraduate Award to D.K.T.)]; the National Institute of Health [R01 RR021885, R01 GM074068, R01 EB008015, P30 HD018655 to S.K.W.]; the United Cerebral Palsy Foundation (USA) to T.E.I.; the Leila Y. Mathers Charitable Foundation (USA) to G.F.E.; the Brown Foundation (USA) to G.F.E.; and the Victorian Government's Operational Infrastructure Support Program to D.K.T., K.J.L., and P.J.A.