Journal article

Progressive myopia or hyperopia can be induced in chicks and reversed by manipulation of the chromaticity of ambient light

WS Foulds, VA Barathi, CD Luu

Investigative Ophthalmology and Visual Science | ASSOC RESEARCH VISION OPHTHALMOLOGY INC | Published : 2013

Abstract

Purpose. To determine whether progressive ametropia can be induced in chicks and reversed by manipulation of the chromaticity of ambient light. Methods. One-day-old chicks were raised in red light (90% red, 10% yellow-green) or in blue light (85% blue, 15% green) with a 12 hour on/off cycle for 14 to 42 days. Refraction was determined by streak retinoscopy, and by automated infrared photoretinoscopy and ocular biometry by A-scan ultrasonography. Results. Red light induced progressive myopia (mean refraction ± SD at 28 days, -2.83 ± 0.25 diopters [D]). Progressive hyperopia was induced by blue light (mean refraction at 28 days, +4.55 ± 0.21 D). The difference in refraction between the groups ..

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University of Melbourne Researchers

Grants

Awarded by Centre Translational Grant from the Singapore National Medical Research Council



Funding Acknowledgements

Supported by Pilot Grants R649/71/2008 and R650/71/2008, and Centre Translational Grant NMRC/CG-SERI/R737-T1 from the Singapore National Medical Research Council. Centre for Eye Research Australia (CERA) receives Operational Infrastructure Support from the Victorian Government.