Journal article
Acquisition of HIV by african-born residents of Victoria, Australia: Insights from molecular epidemiology
C Lemoh, CE Ryan, Z Sekawi, AC Hearps, E Aleksic, D Chibo, J Grierson, S Baho, A Street, M Hellard, BA Biggs, SM Crowe
Plos One | PUBLIC LIBRARY SCIENCE | Published : 2013
Abstract
African-born Australians are a recognised "priority population" in Australia's Sixth National HIV/AIDS Strategy. We compared exposure location and route for African-born people living with HIV (PLHIV) in Victoria, Australia, with HIV-1 pol subtype from drug resistance assays and geographical origin suggested by phylogenetic analysis of env gene. Twenty adult HIV positive African-born Victorian residents were recruited via treating doctors. HIV exposure details were obtained from interviews and case notes. Viral RNA was extracted from participant stored plasma or whole blood. The env V3 region was sequenced and compared to globally representative reference HIV-1 sequences in the Los Alamos Na..
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Funding Acknowledgements
The authors are grateful for the financial and material support provided by the Centre for Clinical Research Excellence in Infectious Diseases and the Department of Medicine; the financial support received from the Victorian Government Department of Human Services, the Victor Hurley Research Fund and the Australasian Society for Infectious Diseases; and the material support provided by the Burnet Institute, the Victorian Infectious Diseases Laboratories and the Victorian Infectious Diseases Service. The authors acknowledge the funding for institutional infrastructure provided by the Victorian Department of Innovation and Industry and the Australian National Health and Medical Research Council. Suzanne Crowe holds a Principal Research Fellowship from the National Health and Medical Research Council. Margaret Hellard holds a Senior Research Fellowship from the National Health and Medical Research Council. The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. The authors gratefully acknowledge the contribution to this work of the Victorian Operational Infrastructure Support Program.