Relative filling time delay based on CT perfusion source imaging: A simple method to predict outcome in acute ischemic stroke

Abstract

BACKGROUND AND PURPOSE: Collateral vessel status is strongly associated with clinical outcome in ischemic stroke but can be challenging to assess. The aim of this study was to develop a tomography perfusion source imaging- based assessment of collateral vessel status. MATERIALS AND METHODS: Consecutive patients with ischemic stroke who received intravenous thrombolysis or intra-arterial reperfusion therapy after CTP were retrospectively analyzed. In those with middle cerebral artery or internal carotid artery occlusion, CT perfusion source imaging was used to identify the relative filling time delay between the normal MCA Sylvian branches and those in the affected hemisphere. Receiver operat..