Insights into the evolution of divergent nucleotide-binding mechanisms among pseudokinases revealed by crystal structures of human and mouse MLKL
James M Murphy, Isabelle S Lucet, Joanne M Hildebrand, Maria C Tanzer, Samuel N Young, Pooja Sharma, Guillaume Lessene, Warren S Alexander, Jeffrey J Babon, John Silke, Peter E Czabotar
Biochemical Journal | PORTLAND PRESS LTD | Published : 2014
Awarded by NHMRC (National Health and Medical Research Council)
Awarded by Australian Research Council
Awarded by NHMRC IRIISS (Independent Medical Research Institutes Infrastructure Support Scheme)
This work was supported by the NHMRC (National Health and Medical Research Council) [grant numbers 637342, 1016647 and 1046984] and fellowships to J.M.H., W.S.A. and J.S.; Australian Research Council fellowships [FT100100100, FT110100169 and FT0992105] to J.M.M., J.J.B. and P.E.C.; a Victorian International Research Scholarship to M.C.T.; with additional support from the Victorian State Government Operational Infrastructure Support and NHMRC IRIISS (Independent Medical Research Institutes Infrastructure Support Scheme) [grant 361646]. J.S. is a member of the Scientific Advisory Board of TetraLogic Pharmaceuticals.