Glaucarubinone and gemcitabine synergistically reduce pancreatic cancer growth via down-regulation of P21-activated kinases
Dannel Yeo, Huynh Nhi, John A Beutler, Christopher Christophi, Arthur Shulkes, Graham S Baldwin, Mehrdad Nikfarjam, Hong He
CANCER LETTERS | ELSEVIER IRELAND LTD | Published : 2014
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Awarded by National Health and Medical Research Council (NHMRC) of Australia
We thank the Drug Synthesis & Chemistry Branch, NCI, for supplying the glaucarubinone used in this study, and Hiroshi Maruta for stimulating discussions. This work was supported by National Health and Medical Research Council (NHMRC) of Australia Grants 508908 (HH) , 1041831 (GB & AS), and 1020983 (GB), by the Austin Hospital Medical Research Foundation, and by the Intramural Research Program of the NIH National Cancer Institute Center for Cancer Research. Dannel Yeo is supported by the Ph.D scholarship from Australian Rotary Health.