Journal article
Positive surgical margins: Rate, contributing factors and impact on further treatment: Findings from the Prostate Cancer Registry
SM Evans, JL Millar, M Frydenberg, DG Murphy, ID Davis, T Spelman, DM Bolton, GG Giles, J Dean, AJ Costello, AG Frauman, PA Kearns, L Day, C Daniels, JJ McNeill
BJU International | Published : 2014
DOI: 10.1111/bju.12509
Abstract
Objective To describe the characteristics of patients with and without positive surgical margins (PSMs) and to analyse the impact of PSMs on secondary cancer treatment after radical prostatectomy (RP), with short-term follow-up. Patients and Methods We analysed data from 2385 consecutive patients treated using RP, who were notified to the Prostate Cancer Registry by 37 hospitals in Victoria, Australia between August 2008 and February 2012. Independent and multivariate models were constructed to predict the likelihood of PSMs. Independent and multivariate predictors of secondary treatment after RP in the initial 12 months after diagnosis were also assessed. Results Data on PSM status were col..
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Funding Acknowledgements
This project was funded by Cancer Australia (Project ID1010384). The authors would like to acknowledge the support provided to the Prostate Cancer Registry by all contributing urologists, radiation oncologists and medical oncologists in contributing hospitals.