Comparative genomics of Cylindrospermopsis raciborskii strains with differential toxicities
Rati Sinha, Leanne A Pearson, Timothy W Davis, Julia Muenchhoff, Ryanbi Pratama, Aaron Jex, Michele A Burford, Brett A Neilan
BMC GENOMICS | BMC | Published : 2014
BACKGROUND: Cylindrospermopsis raciborskii is an invasive filamentous freshwater cyanobacterium, some strains of which produce toxins. Sporadic toxicity may be the result of gene deletion events, the horizontal transfer of toxin biosynthesis gene clusters, or other genomic variables, yet the evolutionary drivers for cyanotoxin production remain a mystery. Through examining the genomes of toxic and non-toxic strains of C. raciborskii, we hoped to gain a better understanding of the degree of similarity between these strains of common geographical origin, and what the primary differences between these strains might be. Additionally, we hoped to ascertain why some cyanobacteria possess the cylin..View full abstract
Awarded by Australian Research Council
This work has been supported by an Australian Research Council grant: LP0989475.