Journal article

Breast Implant-Associated Anaplastic Large-Cell Lymphoma: Long-Term Follow-Up of 60 Patients

Roberto N Miranda, Tariq N Aladily, H Miles Prince, Rashmi Kanagal-Shamanna, Daphne de Jong, Luis E Fayad, Mitual B Amin, Nisreen Haideri, Govind Bhagat, Glen S Brooks, David A Shifrin, Dennis P O'Malley, Chan Y Cheah, Carlos E Bacchi, Gabriela Gualco, Shiyong Li, John A Keech, Ephram P Hochberg, Matthew J Carty, Summer E Hanson Show all

JOURNAL OF CLINICAL ONCOLOGY | AMER SOC CLINICAL ONCOLOGY | Published : 2014

Abstract

PURPOSE: Breast implant-associated anaplastic large-cell lymphoma (ALCL) is a recently described clinicopathologic entity that usually presents as an effusion-associated fibrous capsule surrounding an implant. Less frequently, it presents as a mass. The natural history of this disease and long-term outcomes are unknown. PATIENTS AND METHODS: We reviewed the literature for all published cases of breast implant-associated ALCL from 1997 to December 2012 and contacted corresponding authors to update clinical follow-up. RESULTS: The median overall survival (OS) for 60 patients was 12 years (median follow-up, 2 years; range, 0-14 years). Capsulectomy and implant removal was performed on 56 of 60 ..

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Grants

Awarded by Cancer Center Support Grant from the National Cancer Institute


Awarded by NATIONAL CANCER INSTITUTE


Funding Acknowledgements

Supported in part by Cancer Center Support Grant No. P30 CA016672 from the National Cancer Institute (data analyses).