Journal article

Paramutation-Like Interaction of T-DNA Loci in Arabidopsis

Weiya Xue, Colin Ruprecht, Nathaniel Street, Kian Hematy, Christine Chang, Wolf B Frommer, Staffan Persson, Totte Niittyla

PLOS ONE | PUBLIC LIBRARY SCIENCE | Published : 2012

Abstract

In paramutation, epigenetic information is transferred from one allele to another to create a gene expression state which is stably inherited over generations. Typically, paramutation describes a phenomenon where one allele of a gene down-regulates the expression of another allele. Paramutation has been described in several eukaryotes and is best understood in plants. Here we describe an unexpected paramutation-like trans SALK T-DNA interaction in Arabidopsis. Unlike most of the previously described paramutations, which led to gene silencing, the trans SALK T-DNA interaction caused an increase in the transcript levels of the endogenous gene (COBRA) where the T-DNA was inserted. This increase..

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University of Melbourne Researchers