Journal article

The FRIABLE1 Gene Product Affects Cell Adhesion in Arabidopsis

Lutz Neumetzler, Tania Humphrey, Shelley Lumba, Stephen Snyder, Trevor H Yeats, Bjoern Usadel, Aleksandar Vasilevski, Jignasha Patel, Jocelyn KC Rose, Staffan Persson, Dario Bonetta



Cell adhesion in plants is mediated predominantly by pectins, a group of complex cell wall associated polysaccharides. An Arabidopsis mutant, friable1 (frb1), was identified through a screen of T-DNA insertion lines that exhibited defective cell adhesion. Interestingly, the frb1 plants displayed both cell and organ dissociations and also ectopic defects in organ separation. The FRB1 gene encodes a Golgi-localized, plant specific protein with only weak sequence similarities to known proteins (DUF246). Unlike other cell adhesion deficient mutants, frb1 mutants do not have reduced levels of adhesion related cell wall polymers, such as pectins. Instead, FRB1 affects the abundance of galactose- a..

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University of Melbourne Researchers


Awarded by Max-Planck Gesellschaft; NSF Plant Genome Research Program

Funding Acknowledgements

Natural Sciences and Engineering Research Council of Canada; Max-Planck Gesellschaft; NSF Plant Genome Research Program (DBI-0606595). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.