HIF-1 alpha stimulates aromatase expression driven by prostaglandin E-2 in breast adipose stroma
Nirukshi U Samarajeewa, Fangyuan Yang, Maria M Docanto, Minako Sakurai, Keely M McNamara, Hironobu Sasano, Stephen B Fox, Evan R Simpson, Kristy A Brown
Breast Cancer Research | BIOMED CENTRAL LTD | Published : 2013
Awarded by NHMRC (Australia)
Awarded by NHMRC (Australia) Career Development Award
Awarded by NHMRC (Australia) Senior Principal Research Fellowship
This research was supported by NHMRC (Australia) Project Grant # GNT1005735 to KAB, ERS and SBF, the Victorian Government, through the Victorian Cancer Agency funding of the Victorian Breast Cancer Research Consortium to ERS, KAB and SBF, and by the Victorian Government Operational Infrastructure Support Program. NUS is supported by a Faculty Postgraduate Research Scholarship (FPRS), Monash University (2009-2012). KAB is supported by an NHMRC (Australia) Career Development Award GNT1007714. ERS is supported by an NHMRC (Australia) Senior Principal Research Fellowship GNT0550900. We thank Prof. William G. Kaelin for providing the HA-HIF-1 alpha-pcDNA plasmid, Prof. Dean P. Edwards for providing the aromatase mouse monoclonal antibody 677 and Dr. Trevor Wilson for his technical help with high content screening analyses. PHI Data Audit 12-10.