Olfactory sulcus morphology in established bipolar affective disorder
Tsutomu Takahashi, Gin S Malhi, Yumiko Nakamura, Michio Suzuki, Christos Pantelis
PSYCHIATRY RESEARCH-NEUROIMAGING | ELSEVIER IRELAND LTD | Published : 2014
This MRI study examined the morphology of the olfactory sulcus, a potential marker of early neurodevelopment in 26 patients with bipolar I disorder and 24 matched controls. Bipolar patients had significantly shallower olfactory sulci bilaterally compared to controls, suggesting that neurodevelopmental abnormalities contribute to the neurobiology of bipolar disorder.
Related Projects (1)
Awarded by Japanese Society for the Promotion of Science, Health and Labour Sciences Research Grants
Awarded by NHMRC
Awarded by Grants-in-Aid for Scientific Research
This research was supported in part by Grants-in-Aid for Scientific Research (C) (no. 22591275, 24591699) and Grants-in-Aid for Scientific Research (B) (no. 24390281) from the Japanese Society for the Promotion of Science, Health and Labour Sciences Research Grants (Comprehensive Research on Disability, Health and Welfare, H23-Seishin-Ippan-002 and H23-Seishin-Ippan-009), a Grant from Research Group For Schizophrenia, Japan, and a Research Grant from the JSPS Asian Core Program. Prof. Christos Pantelis was supported by a NHMRC Senior Principal Research Fellowship (ID: 628386), NARSAD Distinguished Investigator Award.