Journal article

Olfactory sulcus morphology in established bipolar affective disorder

Tsutomu Takahashi, Gin S Malhi, Yumiko Nakamura, Michio Suzuki, Christos Pantelis

PSYCHIATRY RESEARCH-NEUROIMAGING | ELSEVIER IRELAND LTD | Published : 2014

Abstract

This MRI study examined the morphology of the olfactory sulcus, a potential marker of early neurodevelopment in 26 patients with bipolar I disorder and 24 matched controls. Bipolar patients had significantly shallower olfactory sulci bilaterally compared to controls, suggesting that neurodevelopmental abnormalities contribute to the neurobiology of bipolar disorder.

University of Melbourne Researchers

Grants

Awarded by Japanese Society for the Promotion of Science, Health and Labour Sciences Research Grants


Awarded by NHMRC


Awarded by Grants-in-Aid for Scientific Research


Funding Acknowledgements

This research was supported in part by Grants-in-Aid for Scientific Research (C) (no. 22591275, 24591699) and Grants-in-Aid for Scientific Research (B) (no. 24390281) from the Japanese Society for the Promotion of Science, Health and Labour Sciences Research Grants (Comprehensive Research on Disability, Health and Welfare, H23-Seishin-Ippan-002 and H23-Seishin-Ippan-009), a Grant from Research Group For Schizophrenia, Japan, and a Research Grant from the JSPS Asian Core Program. Prof. Christos Pantelis was supported by a NHMRC Senior Principal Research Fellowship (ID: 628386), NARSAD Distinguished Investigator Award.